Integrated management of multidrug-resistant tuberculosis, HIV, and hepatitis B co-infection in Ghana: a case report - Summary - MDSpire
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Comprehensive Approach to Managing Co-infection of Multidrug-Resistant Tuberculosis, HIV, and Hepatitis B in Ghana: A Case Study

  • By

  • Stanley Yaidoo

  • Judith Maame Tanoa Yelbert

  • Rodger MacScott-Lutterodt

  • Elizabeth Nkumah Obeng

  • Stephannie Kafui Amenya

  • June 15, 2026

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Objective:

To present a case of a patient co-infected with multidrug-resistant tuberculosis (MDR-TB), HIV, and hepatitis B, highlighting the challenges and management strategies in a resource-limited setting.

Approach:
    Key Findings:
    • The patient completed the MDR-TB regimen with documented microbiological cure.
    • Challenges included adverse drug reactions, chronic renal disease, and interruptions in antiretroviral therapy due to drug stockouts.
    • Integrated, multidisciplinary care is crucial for managing complex co-infections.
    Interpretation:

    The case underscores the complexities of managing co-infections in low-resource settings, emphasizing the need for improved healthcare systems to address drug shortages and financial barriers.

    Limitations:
    • Limited diagnostic capabilities and healthcare access in resource-constrained settings.
    • Financial barriers preventing adequate treatment for hepatitis B and renal disease.
    Conclusion:

    This case highlights the importance of integrated care for patients with complex co-infections and the need for systemic improvements in healthcare delivery.

    Sources:

Original Source(s)

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