Exploring the Determinants of Long COVID in Sub-Saharan Africa: A Scoping Review - Summary - MDSpire

Exploring the Determinants of Long COVID in Sub-Saharan Africa: A Scoping Review

  • By

  • Valdez Jaures Njio Heugno

  • Odette Linda Kamdem

  • Estelle Geraldine Essangui Same

  • Elysée Claude Bika Lele

  • Yves Mbama Biloa

  • Clarisse Ayina Ayina

  • Jessica Guyot

  • Bienvenu Bongue

  • Samuel Honore Mandengue

  • Carole Else Eboumbou Moukoko

  • March 4, 2026

  • 0 min

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Objective:

To identify risk factors associated with long COVID in sub-Saharan Africa, analyze differences from other regions, examine implications for clinical management and public health policy, and identify specific gaps in current knowledge.

Key Findings:
  • Long COVID affects 10% to 30% of patients post-infection, with symptoms persisting beyond the acute phase.
  • Sub-Saharan Africa has unique epidemiological factors, including a youthful population and high prevalence of chronic comorbidities, which complicate management.
  • Fragmentary data on long COVID prevalence and characteristics in sub-Saharan Africa suggests it is a significant health burden.
Interpretation:

The clinical picture of long COVID is heterogeneous, with over 200 documented symptoms, and the region's unique demographics and health challenges complicate management and diagnosis.

Limitations:
  • Limited availability of diagnostic tests and post-COVID rehabilitation programs.
  • Under-diagnosis due to access constraints and variability in health information.
  • Fragmentation of health systems and poor coordination in care.
  • Socio-economic factors may further complicate the management of long COVID.
Conclusion:

There is a critical need for harmonized diagnostic criteria and tailored approaches to manage long COVID in sub-Saharan Africa, alongside further research to fill specific knowledge gaps.

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