Association of the C-reactive protein-triglyceride glucose index with microvascular obstruction and long-term prognosis in patients with acute myocardial infarction: a CMR-based study - Summary - MDSpire
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Association of the C-reactive protein-triglyceride glucose index with microvascular obstruction and long-term prognosis in patients with acute myocardial infarction: a CMR-based study
To evaluate the association between the C-reactive protein-triglyceride glucose index (CTI) and microvascular obstruction (MVO) in acute myocardial infarction (AMI) patients.
Approach:
Population: 967 AMI patients were included, with 255 having diabetes mellitus and 712 without.
Key Findings:
476 patients developed CMR-defined MVO.
Higher baseline CTI levels were significantly associated with an increased risk of MVO (OR = 1.33, 95% CI: 1.13–1.56, P = 0.001).
A linear dose-response relationship was observed between CTI and MVO risk.
During a median follow-up of 43 months, higher CTI levels were associated with an increased risk of long-term MACE, particularly in the non-diabetic subgroup.
Interpretation:
CTI is associated with MVO after PCI in AMI patients and shows prognostic value for long-term MACE, particularly in patients without diabetes.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce selection bias.
Conclusion:
CTI may assist in risk stratification following PCI.
