Chronic Cough Despite Normal Workup - Summary - MDSpire

Chronic Cough Despite Normal Workup

  • By

  • Kathryn Wighton

  • February 13, 2026

  • 2 min

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Objective:

To highlight the diagnosis and management of cough-predominant laryngeal hypersensitivity syndrome in a patient with unexplained chronic cough.

Key Findings:
  • Normal routine investigations can mask laryngeal hypersensitivity syndrome.
  • Flexible bronchoscopy is crucial for diagnosing exaggerated laryngeal sensitivity.
  • Symptoms include chronic cough, throat irritation, and globus sensation.
Interpretation:

Laryngeal hypersensitivity syndrome is often overlooked due to normal findings in standard tests, necessitating targeted evaluations for accurate diagnosis.

Limitations:
  • The study is based on a single patient case, limiting generalizability.
  • Lack of long-term follow-up data on management outcomes.
Conclusion:

This case emphasizes the need to consider laryngeal hypersensitivity syndrome in patients with chronic cough when standard investigations yield no results.

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