Implementation of Exclusive Enteral Nutrition in Pediatric Crohn's Disease: A Secondary Analysis of the CLARA Registry Study - Summary - MDSpire

Implementation of Exclusive Enteral Nutrition in Pediatric Crohn's Disease: A Secondary Analysis of the CLARA Registry Study

  • By

  • Tischler, Luisa

  • Boerkoel, Aletta

  • Cantez, Mustafa Serdar

  • Krause, Heiko

  • De Laffolie, Jan

  • van den Berg, Neeltje

  • May 4, 2026

  • 0 min

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Objective:

To describe real-world patterns of enteral nutrition (EN) use and implementation gaps in children with luminal Crohn's disease (CD) based on a secondary analysis of the CLARA trial.

Key Findings:
  • A non-significant trend toward higher EN use in the intervention group (72.4% vs. 61.5%; p=0.225).
  • EEN for the recommended duration was uncommon in both groups (IG: 9.5%; CG: 18.8%).
  • Steroid use within 90 days was higher in the control group (n=22 vs. n=16; p=0.028).
Interpretation:

Limitations:
  • Limited adherence to guideline recommendations for EEN.
  • Potential structural, professional, and patient-related barriers affecting implementation.
Conclusion:

Original Source(s)

Implementation of Exclusive Enteral Nutrition in Pediatric Crohn's Disease: A Secondary Analysis of the CLARA Registry Study

  • by Tischler, Luisa , Boerkoel, Aletta , Cantez, Mustafa Serdar, Krause, Heiko , De Laffolie, Jan , van den Berg, Neeltje

  • May 4, 2026

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