Social Precariousness and the Outcome of Critical Illnesses in People with HIV: A Multicenter Cohort Study - Summary - MDSpire

Social Precariousness and the Outcome of Critical Illnesses in People with HIV: A Multicenter Cohort Study

  • By

  • Piotr Szychowiak

  • Thierry Boulain

  • Étienne de Montmollin

  • Jean-François Timsit

  • Alexandre Elabbadi

  • Laurent Argaud

  • Stephan Ehrmann

  • Nahema Issa

  • Emmanuel Canet

  • Frédéric Martino

  • Fabrice Bruneel

  • Jean-Pierre Quenot

  • Florent Wallet

  • Élie Azoulay

  • François Barbier

  • November 12, 2025

  • 0 min

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Objective:

To assess the association of social precariousness, defined as socioeconomic instability affecting access to care, with in-hospital and 1-year mortality in HIV-positive individuals requiring ICU admission.

Key Findings:
  • Out of 939 HIV-positive patients, 136 (14.5%) were classified as precarious.
  • Precarious migrants were younger and had fewer comorbidities; others had lower viral suppression rates.
  • Overall in-hospital mortality was 17.8% and 1-year mortality was 24.2%.
  • Precariousness was not independently associated with increased in-hospital or 1-year mortality.
Interpretation:

While precarious HIV-positive patients exhibit distinct clinical features, their social vulnerability does not correlate with higher mortality rates during hospitalization or within one year, highlighting the need for improved healthcare access.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the generalizability of results.
  • Data on long-term health outcomes beyond one year were not assessed.
Conclusion:

Social precariousness in HIV-positive individuals requiring ICU admission is linked to specific clinical characteristics but does not increase mortality risk.

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