To analyze organ support needs and patient outcomes in adult patients hospitalized with hantavirus cardiopulmonary syndrome (HCPS) in Chile.
Approach:
Data Source: Utilized a national hospitalization registry from the Chilean Diagnosis-Related Groups (DRG) system to identify adult HCPS patients in 2024.
Patient Identification: Identified HCPS-related admissions using ICD codes, focusing on organ support strategies and in-hospital outcomes.
Key Findings:
A total of 31 patients were identified, with a median age of 44 years and a male predominance (71%).
In-hospital mortality was 16.1%, with severe cases requiring advanced organ support.
Approximately 25.8% of patients required VA-ECMO, indicating significant organ support needs.
Transfusion requirements were noted in 46.7% of severe cases, and renal replacement therapy was required in 13.3% of severe cases.
Interpretation:
HCPS imposes a considerable demand for advanced organ support, and mortality rates align with previous reports. The need for timely escalation to ECMO support is critical.
Limitations:
Study design limitations include lack of initial disease severity data and details on how organ support was delivered.
Conclusion:
HCPS should be approached as a critical illness with a high likelihood of requiring specialized cardiopulmonary support, emphasizing the importance of early transfer to ECMO-capable centers.
