Environmental Nonessential Element Exposure and Urologic Cancer: A Systematic Review and Meta-Analysis - Summary - MDSpire

Environmental Nonessential Element Exposure and Urologic Cancer: A Systematic Review and Meta-Analysis

  • By

  • Zhengyi Deng

  • Jinhui Li

  • Renyue Ji

  • Juan Ramon Delgado

  • Steve H. L. Yim

  • Linda Kachuri

  • Andres Cardenas

  • Rebecca E. Graff

  • John T. Leppert

  • Leslie K. Dennis

  • Benjamin I. Chung

  • Marvin E. Langston

  • May 22, 2026

  • 0 min

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Objective:

To evaluate associations between exposure to multiple environmental nonessential elements and the risk of individual and overall urologic cancers.

Key Findings:
  • Urologic cancers account for 13.1% of new cancer cases and 7.9% of cancer deaths globally.
  • Nonessential elements like arsenic and cadmium are classified as group 1 carcinogens by the International Agency for Research on Cancer.
  • The effects of low-level environmental exposure to nonessential elements on urologic cancer risk are poorly understood.
Interpretation:

Remove unsupported conclusions and rephrase to reflect the study's findings without editorializing.

Limitations:
  • Limited data on low-level environmental exposure to nonessential elements.
  • Previous meta-analyses often focused on single exposure sources and high-level occupational exposures.
Conclusion:

Revise to avoid suggesting further investigation unless explicitly stated in the source.

Original Source(s)

Environmental Nonessential Element Exposure and Urologic Cancer: A Systematic Review and Meta-Analysis

  • by Zhengyi Deng, Jinhui Li, Renyue Ji, Juan Ramon Delgado, Steve H. L. Yim, Linda Kachuri, Andres Cardenas, Rebecca E. Graff, John T. Leppert, Leslie K. Dennis, Benjamin I. Chung, Marvin E. Langston

  • May 22, 2026

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