Rapid evaporative ionization mass spectrometry in surgery: a systematic review - Summary - MDSpire

Rapid evaporative ionization mass spectrometry in surgery: a systematic review

  • By

  • Angus R J Barber

  • Alexander Dottore

  • James Leigh

  • Mark Fear

  • Fiona Wood

  • November 12, 2025

  • 0 min

Share

Objective:

To discuss the applications and reported outcomes of REIMS technology in a surgical context, highlighting its potential to improve intraoperative tissue identification.

Key Findings:
  • 26 studies were included, originating from seven countries and covering eight surgical specialties, after screening 344 records.
Interpretation:

REIMS shows potential for rapid and accurate intraoperative tissue identification, but current applications are primarily ex vivo, necessitating further in vivo research to validate its effectiveness.

Limitations:
  • Limited in vivo data reported, along with logistical challenges related to equipment and the complexity of data interpretation, which may hinder widespread adoption.
Conclusion:

Further in vivo studies with larger patient cohorts are needed to enhance the application of REIMS in surgical practice.

Original Source(s)

Related Content