Objective:

To determine the efficacy and safety of PreserFlo MicroShunt compared to conventional trabeculectomy in glaucoma patients, focusing on postoperative IOP and complication rates.

Key Findings:

• PreserFlo MicroShunt showed a different efficacy profile compared to trabeculectomy in terms of postoperative IOP, with a mean reduction of X mmHg.
• Surgical success rates varied between the two interventions, with distinct postoperative complication profiles, including Y% hypotony in PreserFlo MicroShunt.

Interpretation:

The findings suggest that while PreserFlo MicroShunt may offer a less invasive alternative to trabeculectomy, differences in efficacy and safety must be carefully considered in clinical decision-making, particularly regarding patient selection.

Limitations:

• Heterogeneity among included studies may affect the generalizability of results, particularly due to variations in study design and patient demographics.
• Potential biases in observational studies could influence outcome assessments, including selection bias and reporting bias.

Conclusion:

PreserFlo MicroShunt presents a promising alternative to trabeculectomy, but further studies are needed to fully understand its long-term efficacy and safety in glaucoma management, particularly in diverse patient populations.