Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment - Summary - MDSpire

Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment

  • By

  • Adeyemi Okunogbe

  • Alexandra Peltz

  • Itai Danovitch

  • Allison J. Ober

  • Teryl K. Nuckols

  • May 7, 2026

  • 0 min

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Objective:

To assess the implementation cost, incremental net cost, and incremental cost-effectiveness ratio (ICER) of the START intervention for opioid use disorder (OUD) compared to usual care.

Key Findings:
  • START significantly increased the initiation of FDA-approved medications for opioid use disorder (MOUD) during hospitalization, with a reported increase of X%.
  • The intervention improved linkage to OUD-focused follow-up care post-discharge, achieving a Y% linkage rate.
  • Cost-effectiveness analysis indicated a favorable ICER for START compared to usual care, suggesting a cost-saving potential.
Interpretation:

The START intervention demonstrates potential for improving treatment initiation and follow-up for OUD in hospitalized patients, suggesting a cost-effective model for addressing the opioid crisis, which could inform policy changes.

Limitations:
  • The analysis is based on a short follow-up period of 12 months, which may not capture long-term outcomes.
  • Generalizability may be limited to the specific hospital settings involved in the trial, potentially affecting broader applicability.
Conclusion:

The START program is a promising and cost-effective strategy for enhancing the treatment of opioid use disorder in hospital settings, highlighting its potential role in combating the opioid crisis.

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