Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma - Summary - MDSpire
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Temporal evolution of the LI-RADS radiation treatment response assessment on multiphase CT/MRI in patients undergoing selective internal radiation therapy for hepatocellular carcinoma
To assess the temporal evolution of the early LI-RADS Radiation TRA version 2024 categories and interobserver agreement on multiphase CT/MRI in patients receiving SIRT for HCC, highlighting its clinical significance.
Key Findings:
The study highlights the gradual evolution of treatment response in HCC post-SIRT, necessitating dynamic imaging evaluations.
The introduction of the LR-TR nonprogressing category allows for better identification of stable or decreasing lesions.
Interobserver agreement on categorizing treatment response features needs further investigation, ideally with quantifiable metrics.
Interpretation:
The findings underscore the importance of the updated LI-RADS algorithm in accurately assessing treatment response in HCC patients undergoing SIRT, given the unique response patterns associated with radiation therapies, which may influence management decisions.
Limitations:
The study is retrospective and conducted at a single center, which may limit generalizability and introduce biases.
Interobserver agreement on imaging feature evaluation was not thoroughly investigated.
Conclusion:
Dynamic evaluation of imaging findings post-SIRT is crucial for optimizing management strategies in HCC treatment, and further research is needed to validate these findings.
