To investigate factors influencing depressive symptoms before and after metabolic and bariatric surgery (MBS) in obese patients and analyze contributing factors to distinct depression trajectories based on preoperative and postoperative data.
Approach:
Key Findings:
Depressive scores significantly decreased at 1, 3, and 6 months postoperatively, indicating effective emotional management.
Anxiety was identified as a consistent risk factor for developing depression in MBS patients.
Higher medication adherence, vitality, role emotional, and resting potential scores were protective against depression progression.
Two heterogeneous subgroups in depression trajectories were identified based on preoperative and postoperative assessments.
Patients with comorbid hypertension and low health transition scores had lower preoperative depression levels.
Patients with comorbid anxiety, low medication adherence, and high vitamin B12 levels exhibited higher preoperative depression levels.
Interpretation:
Patients with anxiety disorder are particularly vulnerable to developing depression after MBS, necessitating tailored interventions for effective emotional management.
Limitations:
The study only included patients from a single hospital, which may limit generalizability.
Exclusion of patients with a history of psychiatric disorders may affect the findings and limit the understanding of depression trajectories.
Conclusion:
Postoperative depression levels significantly decreased in patients with higher preoperative depression severity, underscoring the critical need for thorough postoperative follow-up.
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