Effects of Tai Chi Cloud Hands on balance and resting-state functional connectivity after stroke: an fNIRS study - Summary - MDSpire

Effects of Tai Chi Cloud Hands on balance and resting-state functional connectivity after stroke: an fNIRS study

  • By

  • Jincheng Li

  • Zhenghao Dong

  • Mingxue Fan

  • Xiang Wang

  • Yingli Bi

  • Zhezhe Ma

  • Shiyan Wang

  • Jin Wang

  • Zunke Gong

  • May 7, 2026

  • 0 min

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Objective:

To evaluate the effects of a 2-week Tai Chi Cloud Hands regimen on balance and resting-state functional connectivity in post-stroke patients, specifically focusing on improvements in balance metrics and brain connectivity patterns.

Key Findings:
  • The intervention group showed significant improvements in BBS (adjusted difference = 3.215 points, p < 0.05) and MBI (adjusted difference = 6.056 points, p < 0.05).
  • Notable reductions in COP path length (adjusted difference = -115.816 mm, p < 0.05) and sway area (adjusted difference = -79.480 mm2, p < 0.05) were observed.
  • Enhanced connectivity was found in DLPFC–PreM and PreM–M1 interactions, with decreased SMA–SMA connectivity, indicating potential neural mechanisms underlying balance improvements.
Interpretation:

The Tai Chi Cloud Hands regimen significantly improved balance and functional outcomes in post-stroke patients, alongside specific changes in prefrontal-motor connectivity.

Limitations:
  • The study was limited to a short intervention period of 2 weeks, which may restrict the generalizability of the findings.
  • Findings regarding connectivity should be interpreted as associative rather than mechanistic, highlighting the need for further research.
Conclusion:

Integrating Tai Chi Cloud Hands into conventional rehabilitation enhances balance and daily functioning in post-stroke patients, with associated changes in brain connectivity.

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