Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT) - Summary - MDSpire

Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT)

  • By

  • Mirjam Renovanz

  • Melina Hippler

  • Robert Kuchen

  • Lorenz Doerner

  • David Rieger

  • Joachim P. Steinbach

  • Michael W. Ronellenfitsch

  • Martin Voss

  • Almuth F. Kessler

  • Vera Nickl

  • Martin Misch

  • Julia Sophie Onken

  • Marion Rapp

  • Minou Nadji-Ohl

  • Marcus Mehlitz

  • Jürgen Meixensberger

  • Michael Karl Fehrenbach

  • Naureen Keric

  • Florian Ringel

  • Jan Coburger

  • Carolin Weiß Lucas

  • Jens Wehinger

  • Friederike Schmidt-Graf

  • Jens Gempt

  • Marcos Tatagiba

  • Ghazaleh Tabatabai

  • Melanie Schranz

  • Susanne Singer

  • September 10, 2025

  • 0 min

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Objective:

To determine whether psychosocial assessment in patients with high-grade gliomas (HGG) could be improved by face-to-face evaluations during doctor-patient consultations, and to compare the effectiveness of these evaluations with standard questionnaire-based methods.

Key Findings:
  • The study aimed to improve identification and support of distressed patients with HGG, with evaluations conducted before and after consultations and follow-up assessments at 3 months.
  • Specific metrics on the percentage of patients identified as distressed and receiving care should be included.
Interpretation:

Integrating psychosocial screening into doctor-patient consultations may enhance the identification of patients needing support compared to standard questionnaire-based methods.

Limitations:
  • The study was non-blinded and conducted in a multicenter setting, which may introduce variability affecting the results.
  • The adaptation of screening tools may not fully address the diverse needs of neuro-oncological patients, potentially limiting the effectiveness of the intervention.
Conclusion:

The GLIOPT trial seeks to optimize psychosocial care for neuro-oncological patients by comparing two screening approaches, highlighting the potential benefits of integrating tailored assessments into clinical practice.

Original Source(s)

Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT)

  • by Mirjam Renovanz, Melina Hippler, Robert Kuchen, Lorenz Doerner, David Rieger, Joachim P. Steinbach, Michael W. Ronellenfitsch, Martin Voss, Almuth F. Kessler, Vera Nickl, Martin Misch, Julia Sophie Onken, Marion Rapp, Minou Nadji-Ohl, Marcus Mehlitz, Jürgen Meixensberger, Michael Karl Fehrenbach, Naureen Keric, Florian Ringel, Jan Coburger, Carolin Weiß Lucas, Jens Wehinger, Friederike Schmidt-Graf, Jens Gempt, Marcos Tatagiba, Ghazaleh Tabatabai, Melanie Schranz, Susanne Singer

  • September 10, 2025

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