To investigate the postoperative results of donors undergoing right hepatectomy for adult-to-adult living donor liver transplantation (A2ALDLT) using minimally invasive liver resection (MILR) compared to open liver resection (OLR), focusing on specific outcomes such as blood loss and complication rates.
Key Findings:
A total of 15 studies involving 2094 cases were included, with 553 cases (26.4%) undergoing MILR and 1541 cases (73.6%) undergoing OLR, highlighting the comparative prevalence of each method.
MILR was associated with significantly reduced intraoperative blood loss and shorter postoperative hospitalization compared to OLR, indicating potential benefits for donor safety.
Postoperative complication rates were notably lower in the MILR group, particularly for complications classified as Dindo-Clavien ≥ IIIa, underscoring the advantages of the minimally invasive approach.
Interpretation:
The findings suggest that MILR may offer a safer alternative to OLR for right hepatectomy in living liver donation, potentially reducing donor morbidity.
Limitations:
All included studies were retrospective, which may introduce bias and limit the generalizability of the findings.
Variability in surgical techniques and definitions of complications across studies may affect the consistency of results.
Conclusion:
MILR appears to be a viable and safer option for right hepatectomy in A2ALDLT, warranting further prospective studies to confirm these findings and enhance donor safety.
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Mayo Clinic Children's delivers comprehensive care for children with liver disease, from early evaluation and second opinions to advanced therapies and pediatric liver transplantation.
