Case Report: Preoperative embolization for a large intracranial pheochromocytoma metastasis: a novel approach to minimize intraoperative risk - Summary - MDSpire

Case Report: Preoperative embolization for a large intracranial pheochromocytoma metastasis: a novel approach to minimize intraoperative risk

  • By

  • Lloyd Mulenga Mwibwe

  • Qing Mao

  • Tao Chang

  • Yixuan Zong

  • Yuxin Quan

  • Yu Li

  • Yuan Fang

  • Liyang Zhang

  • Qicheng Shu

  • Siliang Chen

  • Yanhui Liu

  • Bai Xue

  • Fu Min

  • Yuan Yang

  • July 14, 2026

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Objective:

To report the first use of preoperative embolization for an intracranial pheochromocytoma metastasis and its effects on intraoperative risks.

Approach:
  • Case Presentation: A 65-year-old woman with a history of metastatic pheochromocytoma presented with a 7.8 × 6.0 cm hypervascular left parietal mass causing neurological symptoms.
  • Multidisciplinary Planning: A multidisciplinary team planned preoperative alpha-adrenergic blockade and embolization to minimize intraoperative risks.
  • Embolization Procedure: Superselective transarterial embolization was performed, achieving near-complete devascularization of the tumor.
Key Findings:
  • Preoperative embolization was successfully performed for an intracranial pheochromocytoma metastasis.
  • The procedure resulted in reduced intraoperative hemorrhage and catecholamine release.
  • Postoperative outcomes included normalization of catecholamines and significant neurological improvement.
Interpretation:

Limitations:
  • The case represents a single instance and may not be generalizable to all patients with similar conditions.
  • Lack of prior reports on the use of embolization in intracranial pheochromocytoma limits comparative analysis.
Conclusion:

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