Impact of Occupational Therapy on Upper Limb Function and Rehabilitation Results Following Stroke: A Systematic Review and Meta-Analysis - Summary - MDSpire

Impact of Occupational Therapy on Upper Limb Function and Rehabilitation Results Following Stroke: A Systematic Review and Meta-Analysis

  • By

  • Jie Bai

  • Tianyun Liu

  • Xuelian Du

  • Wenrui Huang

  • April 23, 2026

  • 0 min

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Objective:

To evaluate the effects of occupational therapy (OT) on upper limb function, daily living ability, and depressive symptoms in stroke patients through a systematic review and meta-analysis.

Key Findings:
  • OT significantly improved upper limb function (SMD = 1.42, 95% CI 0.62–2.21, p = 0.0005).
  • OT enhanced activities of daily living (SMD = 1.17, 95% CI 0.80–1.54, p < 0.00001).
  • OT reduced depressive symptoms (SMD = -2.08, 95% CI -3.01 to -1.15, p < 0.00001).
  • Larger effects were noted in specific settings and with longer OT durations (>8 weeks).
Interpretation:

OT is effective in improving physical and psychological outcomes in stroke patients, suggesting its essential role in rehabilitation and the need for its integration into clinical practice.

Limitations:
  • The review included only English and Chinese databases, potentially limiting the comprehensiveness of the findings and introducing language bias.
  • Moderate certainty of evidence for all outcomes as assessed by GRADE.
Conclusion:

OT significantly enhances upper limb function, daily living ability, and reduces depressive symptoms in stroke patients, supporting its integration into rehabilitation programs and clinical guidelines.

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