Contact Lens Dropout? Start With the Lids - Summary - MDSpire
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Contact Lens Dropout? Start With the Lids

  • By

  • Pamela E. Theriot, OD

  • September 1, 2026

  • 5 min

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Objective:

To explore the relationship between Demodex infestation, meibomian gland dysfunction (MGD), and contact lens dropout.

Approach:
  • Demodex and MGD Correlation: Investigated the prevalence of Demodex mites and MGD in contact lens wearers, highlighting their impact on comfort and wear time.
  • Diagnosis and Treatment: Described diagnostic methods for Demodex blepharitis and treatment options, including lotilaner and ivermectin.
Key Findings:
  • 93% of soft contact lens dropout patients have Demodex infestation.
  • Less than 6% of patients with Demodex on lid margins report no discomfort.
  • 57% of patients with MGD also have Demodex blepharitis.
  • 60% of contact lens wearers exhibit MGD.
  • Lotilaner 0.25% is FDA-approved for eradicating Demodex mites.
Interpretation:

The presence of Demodex mites and MGD significantly contributes to contact lens discomfort and dropout.

Limitations:
  • The article does not address the long-term efficacy of treatments.
  • Limited discussion on alternative causes of contact lens dropout.
Conclusion:

Effective treatments targeting Demodex and MGD can potentially reduce contact lens dropout rates.

Sources:

Original Source(s)

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