Uterine-Sparing vNOTES vs. laparoscopic lateral suspension for pelvic organ prolapse repair: a prospective comparative study of feasibility and early outcomes - Summary - MDSpire

Uterine-Sparing vNOTES vs. laparoscopic lateral suspension for pelvic organ prolapse repair: a prospective comparative study of feasibility and early outcomes

  • By

  • Abdurrahman Sengi

  • Mehmet Nuri Duran

  • Mayıs Jinda Pekgül

  • Nurullah Peker

  • May 8, 2026

  • 0 min

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Objective:

To evaluate perioperative performance, anatomical correction, and functional outcomes of vNOTES compared to laparoscopic lateral suspension in repairing pelvic organ prolapse.

Key Findings:
  • Both techniques achieved successful anterior-apical correction.
  • vNOTES had significantly shorter operative time (60.4 vs. 90.7 min) and hospital stay (1.32 vs. 1.98 days).
  • POP-Q measurements favored vNOTES at 6 months for Ba and Bp.
  • Lower functional scores (POPDI-6 and UDI-6) were observed in the vNOTES group, indicating potential areas for improvement.
  • No mesh exposures occurred and complication rates were low.
Interpretation:

vNOTES provided faster recovery and greater functional symptom improvement compared to LLS, without compromising safety, highlighting its potential as a preferred option.

Limitations:
  • Short follow-up duration limits assessment of long-term durability.
  • Single-center study may affect generalizability and introduce potential biases.
Conclusion:

Both vNOTES and LLS are effective for uterus-preserving prolapse repair, with vNOTES showing advantages in recovery and functional outcomes.

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