Changes in Body Fat Over Time Following Knee Injuries in Young Athletes: Insights for Preventing Post-Traumatic Osteoarthritis
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By
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Justin M. Losciale
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Nuria EJ Jansen
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Christina Y. Le
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Leo Lu
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Hui Xie
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Marienke van Middelkoop
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Jackie L. Whittaker
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July 13, 2026
Objective:
To compare patterns of adiposity change between youth with a sport-related knee injury and uninjured youth in the 2-year period following injury.
Approach:
- Study Design: Primary analysis of the Alberta Youth Prevention of Early Osteoarthritis Cohort (PrEOA) prospective cohort study.
- Participants: 186 youth (106 injured, 80 uninjured, 62% female, mean age 16±2 years) were assessed for fat mass (FM) at baseline and follow-ups.
- Data Collection: Fat mass was measured using bioelectrical impedance at baseline (≤4 months from injury) and at 6, 12, 18, and 24 months.
- Statistical Analysis: Linear mixed models were used to examine the association between knee injury and FM change over time, adjusting for confounders.
Key Findings:
- No significant differences in FM gain between injured and uninjured groups over 24 months (0.1 kg, 95%CI: -0.6, 0.9).
- Minimal to no differences in FM at any time point (6-months: 0.9, 12-months: 0.7, 18-months: -0.1, 24-months: -0.9).
- No significant differences between individuals with ACL tears versus other knee injuries, or between sexes.
Interpretation:
Adiposity gains of youth with a sport-related knee injury over the initial 2-years post-injury may not differ from uninjured youth.
Limitations:
- The study may not account for all potential confounders affecting adiposity.
- Data on physical activity levels post-injury were not detailed.
Conclusion:
Sources: