To characterize the clinical features of penile melanoma and summarize treatment options through case reports and a literature review.
Approach:
Case Presentation: Three cases of primary penile melanoma were presented, detailing clinical management and outcomes, including surgical interventions and patient prognoses.
Literature Review: Analysis of 27 additional reported cases of penile melanoma to identify common characteristics and treatment approaches, focusing on demographics and clinical presentations.
Key Findings:
Penile melanoma is rare, accounting for less than 2% of penile tumors and less than 0.1% of all melanomas.
Typical manifestations include pigmented patches or nodules on the glans or foreskin.
Surgical treatment is the primary option, with adjuvant therapies like chemotherapy and radiotherapy used to prevent recurrence.
Interpretation:
Penile melanoma requires personalized management strategies, emphasizing the need for complete resection and consideration of systemic therapies.
Limitations:
Lack of established clinical guidelines for the management of penile melanoma limits treatment standardization.
The limited number of cases reported in literature hinders the establishment of standardized protocols.
Conclusion:
Further case reports and clinical research are essential to establish standardized protocols for the management of penile melanoma.
