To identify key anatomical predictors of clinical symptoms and evaluate management patterns in a large pediatric cohort with AAORCA.
Approach:
Statistical Analysis: Multivariable logistic regression was performed to identify factors associated with symptomatic presentation, considering variables such as age and anatomical features.
Key Findings:
Ostial stenosis showed a stronger unadjusted association with symptoms compared to other anatomical features, but no anatomical variable remained independently associated after adjustment.
Interpretation:
Pediatric AAORCA demonstrates significant variability in clinical presentation, anatomical features, and management strategies, complicating risk stratification.
Limitations:
The single-center nature of the study may limit the generalizability of the findings.
The retrospective design may introduce selection and recall bias.
Conclusion:
The study suggests that future research may benefit from phenotype-oriented risk classification frameworks.
