Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach - Summary - MDSpire

Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach

  • By

  • Yuhang Lv

  • Yanting Jiang

  • Kaiyuan Hui

  • Xiaodong Jiang

  • June 11, 2026

  • 0 min

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Objective:

To report a rare case of esophageal squamous cell carcinoma (ESCC) metastasizing to the pancreas and stomach, highlighting its significance in the context of ESCC management.

Key Findings:
  • The patient developed isolated pancreatic and gastric metastases after a prolonged disease-free interval of 37 months.
  • Histopathological analysis confirmed the metastases originated from the primary ESCC.
  • The patient received a systemic regimen of immune checkpoint inhibitors and platinum-based chemotherapy post-surgery, emphasizing the need for tailored treatment strategies.
Interpretation:

This case emphasizes the need to consider rare metastases in patients with a history of ESCC, even after a long disease-free period, and suggests a reevaluation of diagnostic protocols.

Limitations:
  • The rarity of pancreatic metastases from ESCC limits generalizability and may introduce biases.
  • The case is based on a single patient experience, which may not represent broader patient populations.
Conclusion:

Aggressive surgical resection combined with postoperative immunochemotherapy may be a viable treatment strategy for atypical metastatic presentations, underscoring the importance of a multidisciplinary approach.

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