To describe clinical presentation, diagnostic investigations, and treatment strategies for tularemia patients managed at two Austrian centres.
Approach:
Design and setting: Retrospective observational study of patients treated at the Medical University of Vienna from 2005–2024 and at Klinikum Wels Grieskirchen from 2019–2024.
Eligibility: Cases required a compatible clinical presentation and microbiological confirmation by serology, culture, or PCR.
Analysis: Clinical characteristics, diagnostic procedures, treatments, treatment response, and surgical interventions were summarized and compared between monotherapy and combination therapy.
Key Findings:
Of 58 treated individuals, 51 were included in the analysis; 30 were managed in Vienna and 21 in Wels Grieskirchen.
Thirty-seven patients (72.5%) received monotherapy and 14 (27.5%) received combination therapy.
Doxycycline was the most common monotherapy (31 patients, 60.8% of the cohort).
Among patients receiving monotherapy, 10 failures were reported; nine occurred in patients treated with doxycycline.
Interpretation:
The study describes real-world tularemia management at two Austrian centres. The supplied article context does not provide further comparative outcome results.
Limitations:
Retrospective observational design.
Seven of 58 treated individuals were excluded because patient-characteristic and treatment information was unavailable.
The supplied context ends during the results section, so additional findings and study limitations are not available.
