Long-term outcomes of two-stage revision with positive cultures at reimplantation - Summary - MDSpire

Long-term outcomes of two-stage revision with positive cultures at reimplantation

  • By

  • Caterina Rocchi

  • Carmine Fabio Bruno

  • Rocco Cannata

  • Katia Chiappetta

  • Guido Grappiolo

  • Mattia Loppini

  • February 26, 2026

  • 0 min

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Objective:

To evaluate the outcomes of patients undergoing two-stage revision for hip and knee PJIs with at least one positive culture at reimplantation and identify associated risk factors.

Key Findings:
  • 15-30% of cases show persistent positive cultures at reimplantation.
  • Certain pathogens linked to higher failure and mortality rates.
  • Patient-related factors such as older age and higher ASA scores correlate with poorer outcomes.
Interpretation:

Positive cultures at reimplantation may indicate a higher risk of infection recurrence and re-revision, necessitating a tailored approach to patient management.

Limitations:
  • Retrospective design may introduce bias.
  • Limited generalizability due to single-center study.
  • Potential for incomplete data in medical records.
Conclusion:

Understanding the implications of positive cultures at reimplantation is crucial for improving patient outcomes in two-stage revision surgeries.

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