GA Gene Therapy Interest Increases - Summary - MDSpire
Clinical Guidelines

GA Gene Therapy Interest Increases

  • May 1, 2026

  • 2 min

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PulseSight Therapeutics has announced the completion of the last patient, last visit in its phase 1 trial of PST-611, a novel non-viral gene therapy for geographic atrophy associated with dry age-related macular degeneration. The trial, conducted in Paris and Grenoble, evaluated the safety and tolerability of PST-611 in six patients. Results will be presented at the ARVO 2026 meeting by Professor Francine Behar-Cohen, marking a critical step towards the next phase of development. PST-611 targets dysregulated iron homeostasis, potentially preserving visual function and offering a less invasive treatment option.

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