In vivo coronary stent evaluation using photon-counting computed tomography: diagnostic performance - Summary - MDSpire
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Assessment of Coronary Stents in Vivo Through Photon-Counting Computed Tomography: A Study of Diagnostic Efficacy

  • By

  • Pietro G. Lacaita

  • Valentin Bilgeri

  • Philipp Spitaler

  • Benedikt Kindl

  • Wolfgang Dichtl

  • Ivan Lechner

  • Sebastian Reinstadler

  • Guy Friedrich

  • Gerlig Widmann

  • Gudrun M. Feuchtner

  • September 19, 2026

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Objective:

To assess the in vivo diagnostic performance of ultrahigh-resolution photon-counting computed tomography (PCCT) for evaluating coronary stents and to compare its image quality with that of energy-integrating detector computed tomography (EID-CT).

Approach:
  • Study Population: Included consecutive patients undergoing coronary CTA with PCCT and compared with controls who had EID-CT for similar clinical indications.
  • Imaging Techniques: PCCT used a dual-source scanner in ultrahigh-resolution mode, while EID-CT employed a 128-slice dual-source CT.
  • Image Analysis: Stent position documented under AHA-16 classification; subjective image quality graded using a 3-point Likert scale.
Key Findings:
  • PCCT provides higher spatial resolution and lower electronic noise compared to EID-CT.
  • In-stent lumen visibility is improved with PCCT, leading to fewer artifacts from stent struts.
  • Previous studies on PCCT's in vivo performance are limited, with few comparing it to invasive coronary angiography (ICA).
Interpretation:

PCCT may enhance the assessment of coronary stents, particularly in visualizing in-stent lumina and reducing diagnostic challenges associated with EID-CT.

Limitations:
  • The study is retrospective and may have selection bias.
  • Limited sample size and lack of diverse patient demographics may affect generalizability.
Conclusion:

PCCT shows promise for improved diagnostic efficacy in assessing coronary stents, warranting further investigation.

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