Bilateral ovarian masses, massive ascites, and prior appendectomy: must it be ovarian cancer? ——a case report of pseudomyxoma peritonei 24 years after appendectomy - Summary - MDSpire

Bilateral ovarian masses, massive ascites, and prior appendectomy: must it be ovarian cancer? ——a case report of pseudomyxoma peritonei 24 years after appendectomy

  • By

  • Sijie Feng

  • Shurui Yang

  • Kaixuan Yang

  • Xiuzhang Yu

  • Xiaoyu Niu

  • May 22, 2026

  • 0 min

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Objective:

To present a case of pseudomyxoma peritonei (PMP) occurring 24 years after an appendectomy and to highlight the diagnostic challenges associated with its metachronous presentation.

Key Findings:
  • The patient was diagnosed with pseudomyxoma peritonei, despite initial suspicions of ovarian cancer.
  • Intraoperative findings included widespread gelatinous material and nodular implants throughout the peritoneum.
  • The case illustrates the potential for gastrointestinal-origin PMP to present as advanced ovarian masses long after an appendectomy.
Interpretation:

The findings highlight the importance of considering PMP in patients with a history of appendectomy presenting with ovarian masses and ascites.

Limitations:
  • The rarity of metachronous presentations of PMP complicates diagnosis and management.
  • The case is based on a single patient, limiting generalizability.
Conclusion:

Long-term follow-up is important for patients with a history of appendectomy to monitor for potential development of PMP.

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