Case Report: Rare factor V inhibitor found in a patient with ulcerative colitis during latent tuberculosis infection
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By
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Yaodong Wang
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Na Li
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Xiaoxin Li
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Jinchun He
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June 2, 2026
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Objective:
To report a case of a patient with ulcerative colitis and latent tuberculosis infection who developed a high-titer factor V inhibitor.
Key Findings:
- The patient had a high-titer factor V inhibitor associated with ulcerative colitis and latent tuberculosis infection.
- Traditional treatment strategies did not improve the patient's condition until immunomodulatory treatment was initiated.
Interpretation:
Limitations:
- The study is based on a single case, limiting generalizability.
- No gold standard exists for diagnosing latent tuberculosis infection.
Conclusion:
Immunoglobulin therapy was used in this case to address factor V inhibitors.
