To summarize the multimodal imaging characteristics and clinical diagnostic value of multiple myeloma (MM) with renal involvement through a typical case report.
Approach:
Case Presentation: A 67-year-old male with left lumbodorsal pain underwent multimodal imaging, including ultrasound, contrast-enhanced ultrasound, computed tomography, and positron emission tomography-computed tomography, leading to a diagnosis of light-chain MM with renal involvement.
Key Findings:
Multimodal imaging revealed a malignant retroperitoneal mass adjacent to the left kidney, extensive invasion of the left renal lesion, and significantly decreased left renal function.
The patient was diagnosed with Durie-Salmon Stage IIIB, R-ISS Stage III high-risk MM and received multi-line chemotherapy, but died of severe infection 5 months after diagnosis.
Interpretation:
Multimodal imaging is crucial for accurate diagnosis, lesion evaluation, and biopsy guidance in MM with renal involvement.
Limitations:
Extramedullary renal involvement in MM is rare and often misdiagnosed due to lack of specific clinical symptoms and typical imaging manifestations.
Increased awareness and experience among clinicians is necessary for early identification.
Conclusion:
Multimodal imaging is essential for diagnosing MM with renal involvement, providing evidence for clinical treatment and prognosis assessment.
