Local full-thickness excision for sessile adenoma and cT1-2 rectal cancer: long-term oncological outcome - Summary - MDSpire

Local full-thickness excision for sessile adenoma and cT1-2 rectal cancer: long-term oncological outcome

  • By

  • Maria A. Gascon

  • Vicente Aguilella

  • Tomas Martinez

  • Luigi Antinolfi

  • Javier Valencia

  • Jose M. Ramírez

  • June 22, 2022

  • 0 min

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Objective:

To evaluate the perioperative morbidity and long-term oncological survival of local excision using the transanal endoscopic microsurgery (TEM) technique for sessile rectal adenomas and early rectal cancer, highlighting the differences in treatment approaches.

Key Findings:
  • TEM technique demonstrated low local recurrence rates for early distal rectal tumors, indicating its effectiveness.
  • Patients with benign lesions (Group A) required no further treatment post-excision, suggesting a favorable outcome.
  • Patients with high-risk (HR) or stage II lesions (Group B) were offered salvage surgery or adjuvant radiotherapy, highlighting the need for tailored treatment strategies.
Interpretation:

The study supports the use of local excision for selected rectal adenomas and early rectal cancers, emphasizing the importance of careful patient selection and surgical technique.

Limitations:
  • The study is limited to a single institution, which may affect the generalizability of the results; further multicenter studies are needed.
  • Long-term outcomes may vary based on patient demographics and tumor characteristics not fully addressed, which could influence treatment decisions.
Conclusion:

Local full-thickness excision using TEM is a viable option for treating sessile adenomas and early rectal cancer, with favorable long-term oncological outcomes, underscoring the importance of careful patient selection.

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