Association between hemoglobin glycation index and all-cause mortality in patients with non–ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention - Summary - MDSpire

Association between hemoglobin glycation index and all-cause mortality in patients with non–ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention

  • By

  • Haodong Jiang

  • Yanlong Zhao

  • Yuanyuan Zhao

  • Shuai Wang

  • Wenliang Zhai

  • Zhi Liu

  • May 25, 2026

  • 0 min

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Objective:

To investigate the association between hemoglobin glycation index (HGI) and all-cause mortality in NSTEMI patients undergoing PCI.

Key Findings:
  • Higher HGI was associated with more favorable survival.
  • A 1-unit increase in HGI correlated with a 43% lower risk of all-cause mortality (HR=0.57, 95% CI: 0.40–0.82, P=0.002).
  • Patients in the highest HGI tertile had a significantly lower risk of mortality compared to those in the lowest tertile (HR=0.26, 95% CI: 0.10–0.66, P=0.004).
  • RCS analysis indicated a linear inverse association between HGI and mortality.
Interpretation:

Limitations:
  • Single-center study may limit generalizability.
  • Potential confounding factors not fully accounted for.
Conclusion:

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