Emergence of Two New Lineages of the Cosmopolitan Dengue Virus Serotype 2 in Yunnan, China, 2024 - Summary - MDSpire

Emergence of Two New Lineages of the Cosmopolitan Dengue Virus Serotype 2 in Yunnan, China, 2024

  • By

  • Man Li

  • Fen Zeng

  • Wei Chang

  • Mengyuan Zheng

  • Xiaojuan Chen

  • Ziying Wu

  • Li Liu

  • Xueshan Xia

  • Yue Feng

  • August 11, 2025

  • 0 min

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Objective:

To investigate the genetic diversity of the dengue virus (DENV) and identify potential sources of transmission in Xishuangbanna, Yunnan Province in 2024.

Key Findings:
  • DENV infection was detected in 101 of 321 specimens.
  • 81 cases belonged to the cosmopolitan genotype and cosmopolitan_asian-pacific subtype of DENV serotype 2.
  • Two distinct lineages of DENV-2 were identified, likely originating from Thailand and Cambodia.
Interpretation:

The study reveals significant genetic diversity of DENV-2 in Yunnan, indicating complex transmission dynamics and potential risks for future outbreaks.

Limitations:
  • The study was limited to a specific geographical area and timeframe.
  • Further research is needed to explore the full epidemiological impact and transmission pathways.
Conclusion:

This research provides crucial insights into the genetic diversity and transmission sources of DENV-2 in Yunnan, aiding in prevention and control efforts.

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