Benign lesions prolapsing through the anus: a differential diagnostic algorithm and evidence-based surgical management—a narrative review - Summary - MDSpire

Benign lesions prolapsing through the anus: a differential diagnostic algorithm and evidence-based surgical management—a narrative review

  • By

  • Jose Antonio Vergara Torrente

  • Luis Alfonso Huerta

  • Carlos Federico Sanchez

  • Pamela Valdez

  • Alondra Esparza González

  • Gerardo Muñoz Maldonado

  • June 11, 2026

  • 0 min

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Objective:

To characterize the distinctive clinical findings of benign anorectal lesions, identify specific red flags for malignancy, provide a diagnostic algorithm, and stratify therapeutic options based on evidence.

Approach:
    Key Findings:
    • Seven benign entities identified: complete rectal prolapse, mucosal rectal prolapse, internal hemorrhoids, thrombosed hemorrhoids, anal condylomas, hypertrophied anal papilla, and anal canal polyps.
    • Emphasis on identifying red flags that indicate potential malignancy or surgical emergencies, which is crucial for timely intervention.
    • Lack of operational algorithms integrating objective clinical findings into validated decision sequences.
    Interpretation:

    The review highlights the importance of accurate differential diagnosis to avoid delays in managing malignant conditions and surgical emergencies.

    Limitations:
    • Narrative review design limits the generation of a PRISMA flowchart.
    • Exclusion of non-English, Spanish, and Italian literature may limit comprehensiveness and the applicability of findings to diverse populations.
    Conclusion:

    The proposed algorithm prioritizes clinical characteristics to optimize surgical decision-making for benign anorectal lesions, potentially improving patient outcomes.

    Sources:

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