Objective:

To map the scientific output on gastric bypass (GB) by analyzing clinical trials indexed in major databases from 2001 to 2024, with a search conducted in 2025.

Key Findings:

• The number of gastric bypass procedures has increased from 100,092 in 2014 to 598,736 in 2023, highlighting the growing demand for this surgical intervention.
• Over 72,000 publications on gastric bypass were retrieved, indicating significant scientific output in the field and the need for ongoing research.
• Gastric bypass is one of the oldest and most widely performed metabolic bariatric surgery procedures, underscoring its established role in obesity treatment.

Interpretation:

The study highlights the growing body of research on gastric bypass, emphasizing the need for comprehensive bibliometric analysis to understand trends and contributions in this area, which may inform future research directions.

Limitations:

• The analysis is limited to clinical trials published in English, which may exclude relevant studies in other languages.
• PubMed's lack of comprehensive citation count data may affect the completeness of the bibliometric analysis, potentially underrepresenting the impact of certain studies.

Conclusion:

The study provides a systematic overview of gastric bypass clinical trials, identifying key research areas and trends in the field.