Prospective Assessment of Early Outcomes Following Thulium Fiber Laser Enucleation of the Prostate Using SOLTIVE™ SuperPulsed Laser Systems in an Asian Population - Summary - MDSpire
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Prospective Assessment of Early Outcomes Following Thulium Fiber Laser Enucleation of the Prostate Using SOLTIVE™ SuperPulsed Laser Systems in an Asian Population
To evaluate the early safety and feasibility of Thulium fiber laser enucleation of prostate (ThuFLEP) using SOLTIVE™ SuperPulsed Laser Systems in an Asian cohort, highlighting its potential advantages over existing treatments.
Key Findings:
No Clavien-Dindo grade ≥3 complications occurred.
Median operation time was 87 minutes.
87.5% of patients were catheter-free by day 1 and 100% by day 14.
Significant reduction in PSA from 6.05 to 1.20 ng/ml (p<0.001) at 3 months.
At 12 months, median Qmax was 21.9 ml/s and median IPSS was 2.
Median prostate size was 60 ml (IQR 49.8–76.0 ml) and median enucleated adenoma weight was 31 g (IQR 20–39 g).
Interpretation:
ThuFLEP shows promising early safety and feasibility in treating BPH in an Asian population, with effective outcomes in catheter-dependent patients, suggesting potential for broader clinical application.
Limitations:
Small sample size of 32 patients.
Short follow-up duration of 12 months.
Lack of preoperative comparison data for some patients, which limits the ability to assess the full impact of the procedure.
Conclusion:
ThuFLEP demonstrates early safety and feasibility, warranting larger, multicenter studies for confirmation of its efficacy and potential advantages over traditional methods.
by Brian W.H. Siu, David K.W. Leung, Rachel S.K. Wong, Chris H.M. Wong, Alex Q. Liu, Chi Hang Yee, Jeremy Y.C. Teoh, Peter K.F. Chiu, Chi Fai Ng, Ka Lun Lo
