To evaluate coronary inflammation and insulin resistance using FAI and TyG index, and assess their associations with coronary heart disease (CHD) and functional ischemia in patients with MAFLD.
Key Findings:
TyG index and FAI were independent risk factors for CHD and coronary functional ischemia (P<0.05).
Nomogram effectively predicted coronary functional ischemia in MAFLD patients with CHD (AUC 0.904).
FAI and TyG index were positively correlated with CHD and functional ischemia risk.
Interpretation:
The study evaluates the relationship between systemic metabolic dysfunction and local coronary inflammation, with a focus on the nomogram's role in CHD risk stratification in MAFLD patients.
Limitations:
The study is limited to a specific patient population with MAFLD, which may affect generalizability.
Reliance on non-invasive measures may not capture all aspects of coronary health.
Conclusion:
The findings indicate that FAI and TyG index are associated with CHD risk in MAFLD patients.
