Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review - Summary - MDSpire

Investigating the Impact of Frailty and Sarcopenia on Swallowing Difficulties in Patients with Head and Neck Cancer: A Scoping Review

  • By

  • Rishni Perera

  • Elizabeth C. Ward

  • Nicole O'Donnell

  • Paul Yates

  • Rebecca L. Packer

  • July 4, 2026

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Objective:

To synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adult patients with head and neck cancer (HNC), and to identify gaps in the current evidence base.

Approach:
  • Methodology: A scoping review methodology was employed, following the five-step framework by Arksey and O'Malley and refined by the Joanna Briggs Institute.
Key Findings:
  • Head and neck cancer (HNC) is increasingly prevalent, particularly among older adults.
  • Frailty and sarcopenia are common in patients with HNC and can co-exist.
  • Dysphagia is a significant complication in HNC, with incidence rates ranging from 30% to 60%.
  • Emerging evidence suggests that frailty and sarcopenia may be associated with dysphagia in HNC patients.
Interpretation:

The relationship between frailty, sarcopenia, and dysphagia in HNC is complex and not fully understood, necessitating further research.

Limitations:
  • Limited existing evidence on the interplay between frailty, sarcopenia, and dysphagia in HNC.
  • No comprehensive synthesis of literature on this topic has been conducted prior to this review.
Conclusion:

This scoping review aims to consolidate findings on frailty and sarcopenia as potential factors related to dysphagia in HNC, highlighting the need for further investigation.

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