To highlight the diagnostic challenges posed by IgG4-related aortitis, which can mimic acute aortic and coronary syndromes, potentially leading to misdiagnosis and inappropriate management.
Histopathological examination remains the gold standard for diagnosis when imaging and clinical findings are inconclusive, underscoring the need for heightened awareness.
Current diagnostic algorithms for acute aortic syndromes do not include inflammatory aortitides like IgG4-RD, which may lead to misdiagnosis.
Interpretation:
The case illustrates a critical diagnostic blind spot in acute cardiovascular care, emphasizing the need for increased awareness of IgG4-related aortitis in patients presenting with chest pain to prevent misdiagnosis.
Limitations:
The diagnosis of IgG4-related aortitis was only confirmed post-mortem through histopathological analysis, highlighting the challenges in acute settings.
The rarity of IgG4-related aortitis may lead to under-recognition in acute settings, impacting timely diagnosis and treatment.
Conclusion:
IgG4-related aortitis can present similarly to acute coronary and aortic syndromes, necessitating careful consideration in acute cardiovascular evaluations.
by Laura Victoria Torres-Araujo, Valente Fernandez-Badillo, Antonio Jordan-Rios, Rodrigo Gopar-Nieto, Silvia Jimenez-Becerra, Jesus A. Cotes-Millan, Daniel Sierra Lara-Martinez, Benjamin I. Hernandez-Mejia, Moises Jimenez-Santos, Sergio A. Criales-Vera
