Efficacy and Safety of a Topical Skincare Regimen with Tripeptide/Hexapeptide following Aesthetic Procedures: Analysis of Two Randomized, Split-Face Trials in Asian Subjects - Summary - MDSpire

Efficacy and Safety of a Topical Skincare Regimen with Tripeptide/Hexapeptide following Aesthetic Procedures: Analysis of Two Randomized, Split-Face Trials in Asian Subjects

  • By

  • Zhenfeng Liu

  • Zhen Yi

  • Peng Wang

  • Li Wan

  • Li Ye

  • Yijing Chen

  • Yiping Zhong

  • Mengting Qiu

  • Linshan Wu

  • Li Fan

  • Xiaoyan Fu

  • Alan D. Widgerow

  • Yuanmeng Yang

  • Céline Blanché

  • Bin Yang

  • June 20, 2026

  • 0 min

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Objective:

To evaluate the efficacy and safety of a facial serum containing TriHex Technology® for skin recovery following fractional CO2 laser (FCL) and radiofrequency microneedling (RFMN) in Asian subjects.

Approach:
    Key Findings:
    • The serum-treated side showed significantly greater recovery on several parameters after multiplicity correction.
    • High subject satisfaction was reported.
    • Benefits were observed across multiple time points.
    Interpretation:

    The findings indicate that the TriHex Technology® serum may enhance skin recovery post-aesthetic treatments in Asian populations, although further controlled studies are needed.

    Limitations:
    • The study was limited to a single center in China.
    • The sample size and demographic may not fully represent the broader Asian population.
    Conclusion:

    The serum may be a useful adjunct for skin recovery following aesthetic procedures, warranting further investigation.

Original Source(s)

Efficacy and Safety of a Topical Skincare Regimen with Tripeptide/Hexapeptide following Aesthetic Procedures: Analysis of Two Randomized, Split-Face Trials in Asian Subjects

  • by Zhenfeng Liu, Zhen Yi, Peng Wang, Li Wan, Li Ye, Yijing Chen, Yiping Zhong, Mengting Qiu, Linshan Wu, Li Fan, Xiaoyan Fu, Alan D. Widgerow, Yuanmeng Yang, Céline Blanché, Bin Yang

  • June 20, 2026

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