The Clinical Value of Endoscopic Ultrasonography Combined with Endoscopic Treatment for Upper Gastrointestinal Lifting Lesions - Summary - MDSpire

The Clinical Value of Endoscopic Ultrasonography Combined with Endoscopic Treatment for Upper Gastrointestinal Lifting Lesions

  • By

  • Guo, Huanhuan

  • Peng, Bo

  • Xiong, Zhang'e

  • Li, Ziyin

  • April 9, 2026

  • 0 min

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Objective:

To evaluate the combined effect of endoscopic ultrasonography (EUS) and endoscopic intervention in managing upper gastrointestinal (GI) lesions that protrude.

Key Findings:
  • Endoscopic management was successful in 101 out of 106 cases.
  • 2 cases were redirected to surgical intervention during the procedure, and 3 were managed surgically.
  • Pathological categories included polyps (24.53%), inflammatory changes (23.58%), leiomyomas (20.75%), GIST (10.38%), and cysts (9.43%).
  • Diagnostic concordance rate between EUS and pathological diagnosis was 81.13%.
  • EUS sensitivity and specificity for polyps were 92.86% and 98.04%, for leiomyomas 88.00% and 97.06%, and for GIST 73.33% and 98.99%.
Interpretation:

EUS demonstrates high accuracy in diagnosing upper GI protrusions, and endoscopic treatments based on EUS evaluations are clinically safe with low postoperative complications.

Limitations:
  • Single-center study may limit generalizability.
  • Retrospective design may introduce bias.
  • Limited sample size and absence of long-term follow-up.
Conclusion:

EUS is highly effective for diagnosing upper GI protrusions, but improved clinical expertise is needed for less common conditions to minimize misdiagnosis.

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