To evaluate the extent and domains of neurologic sequelae in pediatric cases of dengue-associated acute encephalitis syndrome (DEN-AES) and their implications for treatment and rehabilitation.
Key Findings:
Neurologic sequelae observed in 39.3% of cases (22 out of 56 children assessed).
Severe disabilities noted in 6 children, with 1 postdischarge death.
Cognitive and behavioral impairments were the most common sequelae (37.5%).
5 children required antiepileptic drugs for ongoing seizure management.
34 children fully recovered, scoring 5 on the Liverpool Outcome Score.
Interpretation:
The study highlights significant neurologic sequelae in pediatric patients following dengue-associated encephalitis, indicating a need for early diagnosis, rehabilitation, and public health strategies.
Limitations:
Limited availability of neuroimaging resources.
Retrospective design may introduce bias in data collection.
Potential confounding factors affecting the results were not addressed.
Conclusion:
Neurologic sequelae are prevalent in pediatric DEN-AES cases, emphasizing the necessity for continuous follow-up and rehabilitation policies in dengue-endemic regions, aligning with existing literature on the topic.
