To assess the impact of neighborhood-level socioeconomic disadvantage, including factors such as income, education, and insurance status, on glioblastoma survival and understand how these socioeconomic factors affect outcomes for patients with glioblastoma.
Key Findings:
Median overall survival (mOS) was 13.7 months.
Patients with high neighborhood disadvantage had a higher likelihood of being black and on Medicaid/Medicare, indicating potential disparities in access to care.
Patients in high disadvantage areas were less likely to undergo complete surgical resection.
Interpretation:
Neighborhood-level socioeconomic disadvantage is associated with poorer glioblastoma outcomes, highlighting the need for targeted interventions to address these disparities.
Limitations:
Retrospective design may introduce bias, limiting causal inferences.
Findings may not be generalizable beyond the single center studied.
Conclusion:
This study is the first to report the association of neighborhood-level socioeconomic deprivation with overall survival in glioblastoma, indicating significant disparities in outcomes that warrant further investigation.
