The flu vaccine is working - Summary - MDSpire

The flu vaccine is working

  • By

  • O. Rose Broderick

  • January 16, 2026

  • 0 min

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Objective:

To assess the effectiveness of the current flu vaccine against circulating H3N2 viruses.

Approach:
    Key Findings:
    • The flu vaccine is providing some protection against the H3N2 subclade K viruses.
    • The French study reported a vaccine effectiveness of approximately 36%.
    • The Chinese study indicated a vaccine effectiveness of about 40% against H3N2 influenza.
    Interpretation:

    Despite concerns about the vaccine's effectiveness due to late-emerging virus mutations, current evidence suggests it still offers a moderate level of protection.

    Limitations:
    • The H3N2 subclade K viruses emerged too late to be included in the 2025-2026 flu vaccine.
    • The effectiveness rates may vary based on population and other factors.
    Conclusion:

    The current flu vaccine is effective in providing some level of protection against circulating H3N2 viruses, despite concerns regarding its efficacy due to mutations.

    Sources:

Original Source(s)

The flu vaccine is working

  • by O. Rose Broderick

  • January 16, 2026

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