To explore whether Tpeak-Tend and Tpeak-Tend/QTc could predict ventricular tachycardia (VT) inducibility in patients with suspected Arrhythmogenic Mitral Valve Prolapse (AMVP), emphasizing their clinical relevance.
Approach:
Key Findings:
Mean Tpeak-Tend was 89.6 ± 12.2 ms; prolonged Tpeak-Tend was significantly associated with VA inducibility (p < 0.05).
19 patients (29.2%) exhibited sustained ventricular arrhythmia during programmed stimulation.
Prolonged Tpeak-Tend (> 90 ms) correlated with higher rates of inducible VT/VF (48.4% vs. 11.8%, p < 0.05).
Only previous syncope showed a significant correlation with VA inducibility among known risk factors.
Interpretation:
Tpeak-Tend and Tpeak-Tend/QTc are reliable ECG markers for predicting VT inducibility in patients with AMVP, suggesting their potential utility in clinical risk stratification, particularly in guiding ICD decisions.
Limitations:
Study is retrospective and observational, limiting causal inferences and potential biases.
Sample size may restrict generalizability of findings, necessitating further validation in larger cohorts.
Conclusion:
Tpeak-Tend is a promising predictor of ventricular tachycardia inducibility in AMVP, warranting further prospective studies for validation.
