Hospital caseload thresholds for improved perioperative outcomes during transurethral resection or enucleation of the prostate: results from the GRAND study - Summary - MDSpire

Hospital caseload thresholds for improved perioperative outcomes during transurethral resection or enucleation of the prostate: results from the GRAND study

  • By

  • Nikolaos Pyrgidis

  • Gerald Bastian Schulz

  • Philipp Weinhold

  • Yannic Volz

  • Michael Atzler

  • Leo Federico Stadelmeier

  • Iason Papadopoulos

  • Christian Stief

  • Julian Marcon

  • Patrick Keller

  • June 25, 2026

  • 0 min

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Objective:

To determine an annual hospital volume threshold after which perioperative morbidity improves for TURP, simple prostatectomy, HoLEP, and ThuLEP.

Approach:
  • Data Source: Utilized data from the German Nationwide Inpatient Data (GRAND) registry from 2005 to 2022.
  • Patient Selection: Included patients who underwent TURP, simple prostatectomy, HoLEP, and ThuLEP.
  • Statistical Analysis: Performed ROC analyses to identify optimal annual hospital caseload thresholds for perioperative morbidity outcomes.
Key Findings:
  • 1,084,650 TURP, 90,735 simple prostatectomy, 64,325 HoLEP, and 15,241 ThuLEP surgeries were performed, with varying perioperative morbidity rates across procedures.
  • TURP showed 3.6% incontinence and 1.5% ICU admissions, while simple prostatectomy had 4.3% incontinence and 8% ICU admissions.
Interpretation:

Higher annual hospital volumes are associated with improved perioperative outcomes for various prostate procedures.

Limitations:
  • Study limited to inpatient data and may not capture all relevant outpatient outcomes.
  • Findings may not be generalizable to non-German healthcare settings.
Conclusion:

Identifying specific annual hospital volume thresholds can guide the centralization of surgical procedures to improve patient outcomes.

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