Case report: Successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS - Summary - MDSpire

Case report: Successful non-surgical management of massive isolated tricuspid Libman-Sacks endocarditis in a pregnant patient with SLE and secondary APS

  • By

  • Duan, Jiaoniu

  • Han, Lin

  • Zhao, Wenli

  • Zhang, Gailian

  • May 18, 2026

  • 0 min

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Objective:

To report a case of isolated tricuspid valve Libman-Sacks endocarditis during pregnancy and the effectiveness of non-surgical management.

Key Findings:
  • Intensive immunomodulatory therapy combined with timely anticoagulation can achieve vegetation regression.
  • This case is the first reported instance of non-surgical management of extensive isolated tricuspid LSE in a pregnant patient.
Interpretation:

The case highlights the potential for effective non-invasive treatment strategies in complex clinical scenarios involving pregnant patients with SLE and APS.

Limitations:
  • The rarity of the condition limits generalizability.
  • Long-term outcomes of the treatment strategy remain to be evaluated.
Conclusion:

Intensive medical management can be a viable alternative to surgery in pregnant patients with extensive isolated tricuspid LSE.

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