Hydration Intervention Did Not Reduce Stone Recurrence - Summary - MDSpire

Hydration Intervention Did Not Reduce Stone Recurrence

  • By

  • Kathryn Wighton

  • March 27, 2026

  • 3 min

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Objective:

To evaluate the effectiveness of a multicomponent behavioral intervention aimed at increasing fluid intake specifically to reduce symptomatic kidney stone recurrence.

Key Findings:
  • Symptomatic stone events occurred in 19% of the intervention group vs 20% of the control group, with no significant difference.
  • Urine volume increased in both groups, with the intervention group showing a greater increase (600 mL/day vs 360 mL/day), although the difference diminished over time.
  • Secondary outcomes related to stone growth and new stone formation were similar between groups.
  • Urinary storage symptoms were more common in the intervention group at 6 and 12 months.
Interpretation:

Despite achieving higher urine volumes, the behavioral intervention did not lead to a reduction in symptomatic kidney stone recurrence over 2 years, indicating no correlation between increased urine volume and reduced recurrence.

Limitations:
  • Participants were recruited from tertiary care centers, which may limit generalizability to broader populations.
  • Increased urine volume in the control group may have reduced detectable differences between groups.
  • Additional fluid intake not captured by the smart water bottle was not measured.
Conclusion:

The increase in urine volume from the behavioral intervention did not correlate with a decrease in recurrent symptomatic stone events over the 2-year follow-up.

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