Ten-Year Follow-Up for Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass: A Systematic Review and Meta-Analysis - Summary - MDSpire

Ten-Year Follow-Up for Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass: A Systematic Review and Meta-Analysis

  • By

  • Mohamed Chouky Kamar

  • Pablo Enrique Astudillo Coello

  • Amanda Vitória Rodrigues dos Santos

  • Silviane Leite Melo

  • April 2, 2026

  • 0 min

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Objective:

To synthesize the long-term comparative efficacy of sleeve gastrectomy (SG) versus Roux-en-Y gastric bypass (RYGB) by reviewing and pooling data from studies with 10-year follow-up outcomes, focusing on weight loss and comorbidity remission.

Key Findings:
  • No statistically significant difference in total weight loss (%TWL) between SG and RYGB.
  • No statistically significant difference in excess weight loss (%EWL) between SG and RYGB.
  • Slight non-significant advantage for gastric bypass in both primary weight loss metrics.
  • Similar remission rates for comorbidities were observed, but specific data were not statistically significant.
Interpretation:

The findings suggest that while RYGB may have slight advantages in weight loss metrics, these differences are not statistically significant over a 10-year follow-up.

Limitations:
  • Limited number of studies with 10-year follow-up.
  • Moderate heterogeneity in outcomes, which may affect the reliability of the pooled results.
Conclusion:

Both SG and RYGB appear to have similar long-term outcomes in terms of weight loss and comorbidity remission, with no significant differences observed.

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